Paul Kohlhaas, founder of BIO Protocol, replied to Changpeng Zhao's tweet on the social platform: "Decentralized Science (DeSci) has successfully brought the liquidity of Meme to universities and laboratories around the world to support real scientific research." Previously, Changpeng Zhao, co-founder of Binance, said on social media: "I'm not against Meme, but Meme is getting'a little bit 'weird now. Let's build real applications with blockchain."