Average transaction returns are a good indicator of whether buying low or selling high is really the right time, Santiment said in a post on X. Currently, wallets active in the past 30 days are in the negative range for BTC, ETH, ADA and DOGE, as well as the vast majority of counterfeit products. When MVRV is negative, it means buying or adding to a position, while others are already losing money. Historically, these "blood in the streets" moments are when professional traders make money. Santiment advises investors to trade cautiously and not assume that these opportunity zone signals will lead to an immediate turnaround. But the likelihood suggests that cryptocurrencies will at least see an upturn in the short to medium term, provided that economic or geopolitical factors do not get in the way of momentum.